Faculty of Mathematics, Physics
and Informatics
Comenius University Bratislava

Seminar of Cognitive Science - Vuk Milosevic (14.3.2017)

Tuesday 14.3.2017 at 16:30, Lecture room I/9

09. 03. 2017 21.59 hod.
By: Igor Farkaš

Vuk Milosevic, MD, PhD. (Center for Cognitive Sciences, University of Niš, Serbia):
Cerebrovascular diseases and cognitive impairment

Cerebrovascular diseases including stroke are the second most common cause of death and disability worldwide. One of the most devastating consequences of stroke is a cognitive impairment, which can significantly affect activities of daily living eventually leading to dementia. Dementia due to stroke or other cerebrovascular disease is the most common type of dementia after Alzheimer’s disease. However, even more patients after stroke have milder forms of vascular cognitive impairment which do not fulfill criteria for dementia but do diminish their quality of life. Cognitive syndrome in patients with cerebrovascular diseases is characterized by memory deficit consisting of impaired recall but relative preservation of recognition, dysexecutive syndrome, slowed information processing and mood changes. Our research also showed characteristic changes in the EEG alpha frequency band which correlate with cognitive impairment. Interestingly, vascular dementia and Alzheimer's disease share the same, well-known vascular risk factors: hypertension, diabetes, elevated cholesterol, smoking etc. These data suggest interaction between vascular changes and amyloid pathology and led some researchers to formulate vascular hypotheses of Alzheimer's disease. Controlling vascular risk factors a significant number of dementia cases can be prevented and the burden of this disease can be reduced.